Critical Care Publications

Below are recent publications by faculty members in the Division of Critical Care in the Department of Pediatrics at Northwestern University Feinberg School of Medicine.

Recent PubMed Publications

Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Correction to: Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 Jun 23;. doi:10.1007/s40264-022-01199-8
Dalabih AR, Prodhan P, Harris ZL, Bone MF Employment Opportunities for Pediatric Critical Care Fellowship Trained Physicians in the United States. J Pediatr Intensive Care 2022 Jun;11(2):105-108. doi:10.1055/s-0040-1716908
Zhang X, Lucas AM, Veturi Y, Drivas TG, Bone WP, Verma A, Chung WK, Crosslin D, Denny JC, Hebbring S et al. Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. Nat Commun 2022 Jun 14;13(1):3428. doi:10.1038/s41467-022-30678-w
Eickelberg G, Luo Y, Sanchez-Pinto LN Development and validation of MicrobEx: an open-source package for microbiology culture concept extraction. JAMIA Open 2022 Jul;5(2):ooac026. doi:10.1093/jamiaopen/ooac026
Sanchez-Pinto LN, Bennett TD Evaluation of Machine Learning Models for Clinical Prediction Problems. Pediatr Crit Care Med 2022 05 01;23(5):405-408. doi:10.1097/PCC.0000000000002942
Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 05;45(5):459-476. doi:10.1007/s40264-022-01155-6
Badke CM, Mayampurath A, Sanchez-Pinto LN Multiple Organ Dysfunction Interactions in Critically Ill Children. Front Pediatr 2022;10:874282. doi:10.3389/fped.2022.874282
Liu B, Yi D, Pan J, Dai J, Zhu MM, Zhao YY, Oh SP, Fallon MB, Dai Z Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension. Pulm Circ 2022 Jan;12(1):e12056. doi:10.1002/pul2.12056
Badke CM, Krogh-Jespersen S, Flynn RM, Shukla A, Essner BS, Malakooti MR Virtual Reality in the Pediatric Intensive Care Unit: Patient Emotional and Physiologic Responses. Front Digit Health 2022;4:867961. doi:10.3389/fdgth.2022.867961
Zhang X, Moore CM, Harmacek LD, Domenico J, Rangaraj VR, Ideozu JE, Knapp JR, Woods KJ, Jump S, Jia S et al. CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons. JCI Insight 2022 03 22;7(6). doi:10.1172/jci.insight.152186
Badke CM, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Association Between Heart Rate Variability and Inflammatory Biomarkers in Critically Ill Children. Pediatr Crit Care Med 2022 Jun 01;23(6):e289-e294. doi:10.1097/PCC.0000000000002936
Michelson KN, Adams JG, Faber JMM Navigating Clinical and Business Ethics While Sharing Patient Data. JAMA 2022 Mar 15;327(11):1025-1026. doi:10.1001/jama.2022.1942
Zhou F, Chen H, Li M, Strickland AL, Zheng W, Zhang X The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma. Am J Surg Pathol 2022 03 01;46(3):300-308. doi:10.1097/PAS.0000000000001800
Balcarcel DR, Coates BM, Chong G, Sanchez-Pinto LN Excessive Oxygen Supplementation in the First Day of Mechanical Ventilation Is Associated With Multiple Organ Dysfunction and Death in Critically Ill Children. Pediatr Crit Care Med 2022 02 01;23(2):89-98. doi:10.1097/PCC.0000000000002861
Badke CM, Swigart L, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Autonomic Nervous System Dysfunction Is Associated With Re-hospitalization in Pediatric Septic Shock Survivors. Front Pediatr 2021;9:745844. doi:10.3389/fped.2021.745844
Michelson KN, Klugman CM, Kho AN, Gerke S Ethical Considerations Related to Using Machine Learning-Based Prediction of Mortality in the Pediatric Intensive Care Unit. J Pediatr 2022 Jan 14;. pii:S0022-3476(21)01276-2
Zhang X, Jin H, Huang X, Chaurasiya B, Dong D, Shanley TP, Zhao YY Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA. Cell Rep 2022 01 04;38(1):110196. pii:S2211-1247(21)01700-9
Sanchez-Pinto LN, Bembea MM, Farris RW, Hartman ME, Odetola FO, Spaeder MC, Watson RS, Zimmerman JJ, Bennett TD, Patterns of Organ Dysfunction in Critically Ill Children Based on PODIUM Criteria. Pediatrics 2022 01 01;149(1 Suppl 1):S103-S110. doi:10.1542/peds.2021-052888P
Mithal LB, Arshad M, Swigart LR, Khanolkar A, Ahmed A, Coates BM Mechanisms and modulation of sepsis-induced immune dysfunction in children. Pediatr Res 2022 01;91(2):447-453. doi:10.1038/s41390-021-01879-8
Derrington SF, Magee P, Paquette ET Restoring Justice: Affluence Should Not Determine Children's Access to Critical Care Services. Pediatr Crit Care Med 2021 12 01;22(12):1097-1099. doi:10.1097/PCC.0000000000002841
Dai Z, Cheng J, Liu B, Yi D, Feng A, Wang T, An L, Gao C, Wang Y, Zhu MM et al. Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis. J Am Heart Assoc 2021 11 16;10(22):e022077. doi:10.1161/JAHA.121.022077
Koch CM, Prigge AD, Anekalla KR, Shukla A, Do Umehara HC, Setar L, Chavez J, Abdala-Valencia H, Politanska Y, Markov NS et al. Age-related Differences in the Nasal Mucosal Immune Response to SARS-CoV-2. Am J Respir Cell Mol Biol 2022 02;66(2):206-222. doi:10.1165/rcmb.2021-0292OC
Zhou F, Chen Y, Strickland AL, Chen H, Zhang X Prevalence of genotype-specific human papillomavirus in cytology specimens and cervical biopsies, and its implication in cervical cancer risk stratification: a retrospective study of 10647 cases. J Cancer 2021;12(23):7167-7176. doi:10.7150/jca.60601
Zhang X, Lv J, Liu P, Xie X, Wang M, Liu D, Zhang H, Jin J Poly-IgA Complexes and Disease Severity in IgA Nephropathy. Clin J Am Soc Nephrol 2021 11;16(11):1652-1664. doi:10.2215/CJN.01300121
Mataya L, Ross LF, Ghavam A, Paquette ET Pediatric Intensivist and Pediatric Neurologist Perspectives and Practices on Death by Neurologic Criteria. J Clin Ethics 2021;32(3):195-205. pii:2021323195
Sanchez-Pinto LN, González-Dambrauskas S, Jabornisky R, Naidoo K, Schlapbach LJ, Kissoon N Sepsis hysteria? Not for children. Lancet 2020 10 24;396(10259):1332-1333. pii:S0140-6736(20)32148-6
Zhang X, Ye D, Yang L, Yue Y, Sultan D, Pacia CP, Pang H, Detering L, Heo GS, Luehmann H et al. Magnetic Resonance Imaging-Guided Focused Ultrasound-Based Delivery of Radiolabeled Copper Nanoclusters to Diffuse Intrinsic Pontine Glioma. ACS Appl Nano Mater 2020 Nov 25;3(11):11129-11134. doi:10.1021/acsanm.0c02297
Wald EL, Badke CM, Hintz LK, Spewak M, Sanchez-Pinto LN Vitamin therapy in sepsis. Pediatr Res 2022 01;91(2):328-336. doi:10.1038/s41390-021-01673-6
Barhight MF, Nelson D, Moran T, Christiano J, Sanchez-Pinto LN Association between the use of balanced fluids and outcomes in critically ill children: a before and after study. Crit Care 2021 07 29;25(1):266. doi:10.1186/s13054-021-03705-3
Machut KZ, Gilbart C, Murthy K, Michelson KN Parental Perspectives on Neonatologist Continuity of Care. Adv Neonatal Care 2021 Dec 01;21(6):E162-E170. doi:10.1097/ANC.0000000000000895
Weese-Mayer DE, Leah Harris Z, Paquette ET, Sanchez-Pinto LN In memoriam: Lauren E. Marsillio-Craney (1979-2020). Clin Auton Res 2021 08;31(4):589-590. doi:10.1007/s10286-021-00812-7
Sanchez-Pinto LN, Wald EL Vitamin C, Quo Vadis? Pediatr Crit Care Med 2021 06 01;22(6):588-590. doi:10.1097/PCC.0000000000002718
Kolaitis IN, Fry JT, Paquette ET How Suboptimal Consolidation of Care During the COVID-19 Pandemic Can Teach Us to Do Better. Hosp Pediatr 2021 08;11(8):e156-e158. doi:10.1542/hpeds.2021-006081
Rissman L, Derrington S, Rychlik K, Michelson KN Parent and Physician Report of Discussions About Prognosis for Critically Ill Children. Pediatr Crit Care Med 2021 09 01;22(9):785-794. doi:10.1097/PCC.0000000000002764
Wynn JL, Mayampurath A, Carey K, Slattery S, Andrews B, Sanchez-Pinto LN Multicenter Validation of the Neonatal Sequential Organ Failure Assessment Score for Prognosis in the Neonatal Intensive Care Unit. J Pediatr 2021 09;236:297-300.e1. pii:S0022-3476(21)00460-1
Ye J, Sanchez-Pinto LN Three Data-Driven Phenotypes of Multiple Organ Dysfunction Syndrome Preserved from Early Childhood to Middle Adulthood. AMIA Annu Symp Proc 2020;2020:1345-1353
Zhao Y, Xiao W, Peng W, Huang Q, Wu K, Evans CE, Liu X, Jin H Oridonin-Loaded Nanoparticles Inhibit Breast Cancer Progression Through Regulation of ROS-Related Nrf2 Signaling Pathway. Front Bioeng Biotechnol 2021;9:600579. doi:10.3389/fbioe.2021.600579
Yi D, Liu B, Wang T, Liao Q, Zhu MM, Zhao YY, Dai Z Endothelial Autocrine Signaling through CXCL12/CXCR4/FoxM1 Axis Contributes to Severe Pulmonary Arterial Hypertension. Int J Mol Sci 2021 Mar 20;22(6). pii:3182
Murday P, Downing K, Gaab E, Misasi J, Michelson KN A Qualitative Study Describing Pediatric Palliative Care in Non-Metropolitan Areas of Illinois. Am J Hosp Palliat Care 2022 Jan;39(1):18-26. doi:10.1177/10499091211005700
Barhight MF, Nelson D, Chong G, Basu RK, Sanchez-Pinto LN Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children. Pediatr Res 2022 01;91(1):235-240. doi:10.1038/s41390-021-01456-z
Badke CM, Marsillio LE, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Development of a Heart Rate Variability Risk Score to Predict Organ Dysfunction and Death in Critically Ill Children. Pediatr Crit Care Med 2021 08 01;22(8):e437-e447. doi:10.1097/PCC.0000000000002707
Kane JM, Hall M, Cecil C, Montgomery VL, Rakes LC, Rogerson C, Stockwell JA, Slain KN, Goodman DM Resources and Costs Associated With Repeated Admissions to PICUs. Crit Care Explor 2021 Feb;3(2):e0347. doi:10.1097/CCE.0000000000000347
Paquette ET In the Wake of a Pandemic: Revisiting School Approaches to Nonmedical Exemptions to Mandatory Vaccination in the US. J Pediatr 2021 04;231:17-23. pii:S0022-3476(21)00029-9
Sanchez-Pinto LN, Parker WF, Mayampurath A, Derrington S, Michelson KN Evaluation of Organ Dysfunction Scores for Allocation of Scarce Resources in Critically Ill Children and Adults During a Healthcare Crisis. Crit Care Med 2021 02 01;49(2):271-281. doi:10.1097/CCM.0000000000004774
Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, Chan ER, Wang Q, Xu R, Flanagan ME et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv 2020 12;6(49). pii:eabb8680
Patel A, Feltman DM, Paquette ET Integrating Public Health Ethics into Shared Decision Making for Children During the Novel Coronavirus Disease-19 Pandemic. J Pediatr 2021 04;231:259-264. pii:S0022-3476(20)31473-6
Foster CC, Paquette ET Improving Advance Care Planning for Seriously Ill Children: Engaging a Diverse Research Population Early and Often. J Pediatr 2021 02;229:16-18. pii:S0022-3476(20)31357-3
Rissman L, Paquette ET Ethical and legal considerations related to disorders of consciousness. Curr Opin Pediatr 2020 12;32(6):765-771. doi:10.1097/MOP.0000000000000961
Wald EL A Fine Line. JAMA 2020 Oct 20;324(15):1501. doi:10.1001/jama.2020.19331
Paquette ET, Derrington S, Fry JT, Michelson K, Patel A, Shah S, Frader JE Shifting Duties of Children's Hospitals During the COVID-19 Pandemic. J Hosp Med 2020 10;15(10):631-633. doi:10.12788/jhm.3490