Critical Care Publications

Below are recent publications by faculty members in the Division of Critical Care in the Department of Pediatrics at Northwestern University Feinberg School of Medicine.

Recent PubMed Publications

Goodman DM, Casale MT, Rychlik K, Carroll MS, Auger KA, Smith TL, Cartland J, Davis MM Development and Validation of an Integrated Suite of Prediction Models for All-Cause 30-Day Readmissions of Children and Adolescents Aged 0 to 18 Years. JAMA Netw Open 2022 Nov 01;5(11):e2241513. pii:e2241513
Walker SB, Badke CM, Carroll MS, Honegger KS, Fawcett A, Weese-Mayer DE, Sanchez-Pinto LN Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children. Pediatr Res 2022 Nov 03;. doi:10.1038/s41390-022-02359-3
Koch CM, Prigge AD, Setar L, Anekalla KR, Do-Umehara HC, Abdala-Valencia H, Politanska Y, Shukla A, Chavez J, Hahn GR et al. Cilia-related gene signature in the nasal mucosa correlates with disease severity and outcomes in critical respiratory syncytial virus bronchiolitis. Front Immunol 2022;13:924792. pii:924792
Paquette ET Reckoning With Redlining and Other Structural Barriers to Health of Critically Ill Children: Addressing Systemic Racism Will Require Shifting the Focus From Micro- to Macrolevel Analysis of Social Risks. Pediatr Crit Care Med 2022 Aug 01;23(8):662-665. doi:10.1097/PCC.0000000000003016
Smith CM Late-Onset Neurologic Dysfunction in Pediatric Sepsis-What Brains Might Learn From Kidneys and Persistent Acute Kidney Injury. Pediatr Crit Care Med 2022 Aug 01;23(8):659-661. doi:10.1097/PCC.0000000000003007
Michelson KN, Arenson M, Charleston E, Clayman ML, Brazg T, Rychlik K, Rosenberg AR, Frader J Parental Views of Social Worker and Chaplain Involvement in Care and Decision Making for Critically Ill Children with Cancer. Children (Basel) 2022 Aug 26;9(9). pii:1287
Madrigal V, MacDuffie K, Paquette ET Addressing Racism in the Healthcare Encounter: The Role of Clinical Ethics Consultants. J Clin Ethics 2022;33(3):202-209
Perizes EN, Chong G, Sanchez-Pinto LN Derivation and Validation of Vasoactive Inotrope Score Trajectory Groups in Critically Ill Children With Shock. Pediatr Crit Care Med 2022 Dec 01;23(12):1017-1026. doi:10.1097/PCC.0000000000003070
Zhang X, Liu SH, Geron M, Mathilda Chiu YH, Gershon R, Ho E, Huddleston K, Just AC, Kloog I, Coull BA et al. Prenatal exposure to PM2.5 and childhood cognition: Accounting for between-site heterogeneity in a pooled analysis of ECHO cohorts in the Northeastern United States. Environ Res 2022 Nov;214(Pt 4):114163. doi:10.1016/j.envres.2022.114163
Zhang X, Lv J, Liu P, Xie X, Li X, Zhang H, Jin J Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis. Bio Protoc 2022 Jul 05;12(13). pii:e4463
Pendergrast TR, Chapin CA, Kriegermeier AA, Pardo AC, Bass LM, Sanchez-Pinto LN Heart rate variability is associated with encephalopathy and outcomes in pediatric acute liver failure. Pediatr Res 2022 Aug 04;. doi:10.1038/s41390-022-02225-2
Zhang X, Yamada Y, Sagayama H, Ainslie PN, Blaak EE, Buchowski MS, Close GL, Cooper JA, Das SK, Dugas LR et al. Human total, basal and activity energy expenditures are independent of ambient environmental temperature. iScience 2022 Aug 19;25(8):104682. pii:104682
Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Correction to: Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 Aug;45(8):927. doi:10.1007/s40264-022-01199-8
Zhang X, Lucas AM, Veturi Y, Drivas TG, Bone WP, Verma A, Chung WK, Crosslin D, Denny JC, Hebbring S et al. Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. Nat Commun 2022 Jun 14;13(1):3428. pii:3428
Eickelberg G, Luo Y, Sanchez-Pinto LN Development and validation of MicrobEx: an open-source package for microbiology culture concept extraction. JAMIA Open 2022 Jul;5(2):ooac026. pii:ooac026
Sanchez-Pinto LN, Bennett TD Evaluation of Machine Learning Models for Clinical Prediction Problems. Pediatr Crit Care Med 2022 May 01;23(5):405-408. doi:10.1097/PCC.0000000000002942
Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 May;45(5):459-476. doi:10.1007/s40264-022-01155-6
Badke CM, Mayampurath A, Sanchez-Pinto LN Multiple Organ Dysfunction Interactions in Critically Ill Children. Front Pediatr 2022;10:874282. pii:874282
Liu B, Yi D, Pan J, Dai J, Zhu MM, Zhao YY, Oh SP, Fallon MB, Dai Z Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension. Pulm Circ 2022 Jan;12(1):e12056. pii:e12056
Badke CM, Krogh-Jespersen S, Flynn RM, Shukla A, Essner BS, Malakooti MR Virtual Reality in the Pediatric Intensive Care Unit: Patient Emotional and Physiologic Responses. Front Digit Health 2022;4:867961. pii:867961
Zhang X, Moore CM, Harmacek LD, Domenico J, Rangaraj VR, Ideozu JE, Knapp JR, Woods KJ, Jump S, Jia S et al. CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons. JCI Insight 2022 Mar 22;7(6). pii:e152186
Badke CM, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Association Between Heart Rate Variability and Inflammatory Biomarkers in Critically Ill Children. Pediatr Crit Care Med 2022 Jun 01;23(6):e289-e294. doi:10.1097/PCC.0000000000002936
Michelson KN, Adams JG, Faber JMM Navigating Clinical and Business Ethics While Sharing Patient Data. JAMA 2022 Mar 15;327(11):1025-1026. doi:10.1001/jama.2022.1942
Zhou F, Chen H, Li M, Strickland AL, Zheng W, Zhang X The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma. Am J Surg Pathol 2022 Mar 01;46(3):300-308. doi:10.1097/PAS.0000000000001800
Balcarcel DR, Coates BM, Chong G, Sanchez-Pinto LN Excessive Oxygen Supplementation in the First Day of Mechanical Ventilation Is Associated With Multiple Organ Dysfunction and Death in Critically Ill Children. Pediatr Crit Care Med 2022 Feb 01;23(2):89-98. doi:10.1097/PCC.0000000000002861
Badke CM, Swigart L, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Autonomic Nervous System Dysfunction Is Associated With Re-hospitalization in Pediatric Septic Shock Survivors. Front Pediatr 2021;9:745844. pii:745844
Michelson KN, Klugman CM, Kho AN, Gerke S Ethical Considerations Related to Using Machine Learning-Based Prediction of Mortality in the Pediatric Intensive Care Unit. J Pediatr 2022 Aug;247:125-128. doi:10.1016/j.jpeds.2021.12.069
Zhang X, Jin H, Huang X, Chaurasiya B, Dong D, Shanley TP, Zhao YY Robust genome editing in adult vascular endothelium by nanoparticle delivery of CRISPR-Cas9 plasmid DNA. Cell Rep 2022 Jan 04;38(1):110196. doi:10.1016/j.celrep.2021.110196
Sanchez-Pinto LN, Bembea MM, Farris RW, Hartman ME, Odetola FO, Spaeder MC, Watson RS, Zimmerman JJ, Bennett TD, Patterns of Organ Dysfunction in Critically Ill Children Based on PODIUM Criteria. Pediatrics 2022 Jan 01;149(1 Suppl 1):S103-S110. doi:10.1542/peds.2021-052888P
Mithal LB, Arshad M, Swigart LR, Khanolkar A, Ahmed A, Coates BM Mechanisms and modulation of sepsis-induced immune dysfunction in children. Pediatr Res 2022 Jan;91(2):447-453. doi:10.1038/s41390-021-01879-8
Derrington SF, Magee P, Paquette ET Restoring Justice: Affluence Should Not Determine Children's Access to Critical Care Services. Pediatr Crit Care Med 2021 Dec 01;22(12):1097-1099. doi:10.1097/PCC.0000000000002841
Dai Z, Cheng J, Liu B, Yi D, Feng A, Wang T, An L, Gao C, Wang Y, Zhu MM et al. Loss of Endothelial Hypoxia Inducible Factor-Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis. J Am Heart Assoc 2021 Nov 16;10(22):e022077. pii:e022077
Koch CM, Prigge AD, Anekalla KR, Shukla A, Do Umehara HC, Setar L, Chavez J, Abdala-Valencia H, Politanska Y, Markov NS et al. Age-related Differences in the Nasal Mucosal Immune Response to SARS-CoV-2. Am J Respir Cell Mol Biol 2022 Feb;66(2):206-222. doi:10.1165/rcmb.2021-0292OC
Zhou F, Chen Y, Strickland AL, Chen H, Zhang X Prevalence of genotype-specific human papillomavirus in cytology specimens and cervical biopsies, and its implication in cervical cancer risk stratification: a retrospective study of 10647 cases. J Cancer 2021;12(23):7167-7176. doi:10.7150/jca.60601
Zhang X, Lv J, Liu P, Xie X, Wang M, Liu D, Zhang H, Jin J Poly-IgA Complexes and Disease Severity in IgA Nephropathy. Clin J Am Soc Nephrol 2021 Nov;16(11):1652-1664. doi:10.2215/CJN.01300121
Mataya L, Ross LF, Ghavam A, Paquette ET Pediatric Intensivist and Pediatric Neurologist Perspectives and Practices on Death by Neurologic Criteria. J Clin Ethics 2021;32(3):195-205. pii:2021323195
Sanchez-Pinto LN, González-Dambrauskas S, Jabornisky R, Naidoo K, Schlapbach LJ, Kissoon N Sepsis hysteria? Not for children. Lancet 2020 Oct 24;396(10259):1332-1333. doi:10.1016/S0140-6736(20)32148-6
Zhang X, Ye D, Yang L, Yue Y, Sultan D, Pacia CP, Pang H, Detering L, Heo GS, Luehmann H et al. Magnetic Resonance Imaging-Guided Focused Ultrasound-Based Delivery of Radiolabeled Copper Nanoclusters to Diffuse Intrinsic Pontine Glioma. ACS Appl Nano Mater 2020 Nov 25;3(11):11129-11134. doi:10.1021/acsanm.0c02297
Wald EL, Badke CM, Hintz LK, Spewak M, Sanchez-Pinto LN Vitamin therapy in sepsis. Pediatr Res 2022 Jan;91(2):328-336. doi:10.1038/s41390-021-01673-6
Barhight MF, Nelson D, Moran T, Christiano J, Sanchez-Pinto LN Association between the use of balanced fluids and outcomes in critically ill children: a before and after study. Crit Care 2021 Jul 29;25(1):266. pii:266
Machut KZ, Gilbart C, Murthy K, Michelson KN Parental Perspectives on Neonatologist Continuity of Care. Adv Neonatal Care 2021 Dec 01;21(6):E162-E170. doi:10.1097/ANC.0000000000000895
Weese-Mayer DE, Leah Harris Z, Paquette ET, Sanchez-Pinto LN In memoriam: Lauren E. Marsillio-Craney (1979-2020). Clin Auton Res 2021 Aug;31(4):589-590. doi:10.1007/s10286-021-00812-7
Sanchez-Pinto LN, Wald EL Vitamin C, Quo Vadis? Pediatr Crit Care Med 2021 Jun 01;22(6):588-590. doi:10.1097/PCC.0000000000002718
Kolaitis IN, Fry JT, Paquette ET How Suboptimal Consolidation of Care During the COVID-19 Pandemic Can Teach Us to Do Better. Hosp Pediatr 2021 Aug;11(8):e156-e158. doi:10.1542/hpeds.2021-006081
Rissman L, Derrington S, Rychlik K, Michelson KN Parent and Physician Report of Discussions About Prognosis for Critically Ill Children. Pediatr Crit Care Med 2021 Sep 01;22(9):785-794. doi:10.1097/PCC.0000000000002764
Wynn JL, Mayampurath A, Carey K, Slattery S, Andrews B, Sanchez-Pinto LN Multicenter Validation of the Neonatal Sequential Organ Failure Assessment Score for Prognosis in the Neonatal Intensive Care Unit. J Pediatr 2021 Sep;236:297-300.e1. doi:10.1016/j.jpeds.2021.05.037
Ye J, Sanchez-Pinto LN Three Data-Driven Phenotypes of Multiple Organ Dysfunction Syndrome Preserved from Early Childhood to Middle Adulthood. AMIA Annu Symp Proc 2020;2020:1345-1353
Zhao Y, Xiao W, Peng W, Huang Q, Wu K, Evans CE, Liu X, Jin H Oridonin-Loaded Nanoparticles Inhibit Breast Cancer Progression Through Regulation of ROS-Related Nrf2 Signaling Pathway. Front Bioeng Biotechnol 2021;9:600579. pii:600579
Yi D, Liu B, Wang T, Liao Q, Zhu MM, Zhao YY, Dai Z Endothelial Autocrine Signaling through CXCL12/CXCR4/FoxM1 Axis Contributes to Severe Pulmonary Arterial Hypertension. Int J Mol Sci 2021 Mar 20;22(6). pii:3182
Murday P, Downing K, Gaab E, Misasi J, Michelson KN A Qualitative Study Describing Pediatric Palliative Care in Non-Metropolitan Areas of Illinois. Am J Hosp Palliat Care 2022 Jan;39(1):18-26. doi:10.1177/10499091211005700