Critical Care Publications
Below are recent publications by faculty members in the Division of Critical Care in the Department of Pediatrics at Northwestern University Feinberg School of Medicine.
Recent PubMed Publications
- Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ et al. Biomarker Assessment of a High-Risk, Data-Driven Pediatric Sepsis Phenotype Characterized by Persistent Hypoxemia, Encephalopathy, and Shock. Pediatr Crit Care Med 2024 Mar 11;. doi:10.1097/PCC.0000000000003499
- Sanchez-Pinto LN, Bennett TD, DeWitt PE, Russell S, Rebull MN, Martin B, Akech S, Albers DJ, Alpern ER, Balamuth F et al. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA 2024 Feb 27;331(8):675-686. doi:10.1001/jama.2024.0196
- Rissman L, Paquette ET Family Challenges and Navigator Support: It is Time We Support Our Families Better. Pediatr Crit Care Med 2024 Feb 01;25(2):180-182. doi:10.1097/PCC.0000000000003403
- Tager JB, Hinojosa JT, LiaBraaten BM, Balistreri KA, Aniciete D, Charleston E, Frader JE, White DB, Clayman ML, Sorce LR et al. Challenges of Families of Patients Hospitalized in the PICU: A Preplanned Secondary Analysis From the Navigate Dataset. Pediatr Crit Care Med 2024 Feb 01;25(2):128-138. doi:10.1097/PCC.0000000000003385
- Walker SB, Winters JM, Schauer JM, Murphy P, Fawcett A, Sanchez-Pinto LN Performance of Tools and Measures to Predict Fluid Responsiveness in Pediatric Shock and Critical Illness: A Systematic Review and Meta-Analysis. Pediatr Crit Care Med 2024 Jan 01;25(1):24-36. doi:10.1097/PCC.0000000000003320
- Prigge AD, Coates BM Can Airway Monocytes from Premature Infants Teach Us about Macrophage Differentiation in the Lungs? Am J Respir Cell Mol Biol 2023 Dec;69(6):612-613. doi:10.1165/rcmb.2023-0305ED
- Rogerson CM, Abu-Sultaneh S, Loberger JM, Ross P, Khemani RG, Sanchez-Pinto LN Predicting Duration of Invasive Mechanical Ventilation in the Pediatric ICU. Respir Care 2023 Nov 25;68(12):1623-1630. doi:10.4187/respcare.11015
- Dai Z, Thorp EB New Way to Study Pulmonary Hypertension in HFpEF. Circ Res 2023 Nov 10;133(11):899-901. doi:10.1161/CIRCRESAHA.123.323753
- Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R et al. Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study. EClinicalMedicine 2023 Nov;65:102252. pii:102252
- Zhao Y, Li C, Zhang S, Cheng J, Liu Y, Han X, Wang Y, Wang Y Inhaled nitric oxide: can it serve as a savior for COVID-19 and related respiratory and cardiovascular diseases? Front Microbiol 2023;14:1277552. pii:1277552
- Sanchez-Pinto LN, Bhavani SV, Atreya MR, Sinha P Leveraging Data Science and Novel Technologies to Develop and Implement Precision Medicine Strategies in Critical Care. Crit Care Clin 2023 Oct;39(4):627-646. doi:10.1016/j.ccc.2023.03.002
- Machut KZ, Gilbart C, Murthy K, Michelson KN A Qualitative Study of Nurses' Perspectives on Neonatologist Continuity of Care. Adv Neonatal Care 2023 Oct 01;23(5):467-477. doi:10.1097/ANC.0000000000001096
- Sanchez-Pinto LN, Bennett TD, Stroup EK, Luo Y, Atreya M, Bubeck Wardenburg J, Chong G, Geva A, Faustino EVS, Farris RW et al. Derivation, Validation, and Clinical Relevance of a Pediatric Sepsis Phenotype With Persistent Hypoxemia, Encephalopathy, and Shock. Pediatr Crit Care Med 2023 Oct 01;24(10):795-806. doi:10.1097/PCC.0000000000003292
- Zhou Z, Zhang Y, Tan C, Zhang J, Yi G, Wang B, Li Y, Lu H, Lu W, Zhang X The long non-coding RNA BBOX1 antisense RNA 1 is upregulated in polycystic ovary syndrome (PCOS) and suppresses the role of microRNA-19b in the proliferation of ovarian granulose cells : Short title: BBOX1 antisense RNA 1 in cell proliferation. BMC Womens Health 2023 Sep 21;23(1):508. pii:508
- Stephen RJ, Lucey K, Carroll MS, Hoge J, Maciorowski K, Jones RC, O'Connell M, Schwab C, Rojas J, Sanchez Pinto LN Sepsis Prediction in Hospitalized Children: Clinical Decision Support Design and Deployment. Hosp Pediatr 2023 Sep 01;13(9):751-759. doi:10.1542/hpeds.2023-007218
- Stephen RJ, Carroll MS, Hoge J, Maciorowski K, Jones RC, Lucey K, O'Connell M, Schwab C, Rojas J, Sanchez-Pinto LN Sepsis Prediction in Hospitalized Children: Model Development and Validation. Hosp Pediatr 2023 Sep 01;13(9):760-767. doi:10.1542/hpeds.2022-006964
- Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS et al. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. medRxiv 2023 Aug 22;. pii:2023.08.21.23293271
- Atreya MR, Bennett TD, Geva A, Faustino EVS, Rogerson CM, Lutfi R, Cvijanovich NZ, Bigham MT, Nowak J, Schwarz AJ et al. External validation and biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock. Res Sq 2023 Aug 02;. pii:rs.3.rs-3216613
- Zhang X, Young C, Liao XH, Refetoff S, Torres M, Tomer Y, Stefan-Lifshitz M, Zhang H, Larkin D, Fang D et al. Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland. JCI Insight 2023 Jun 22;8(12). pii:e169937
- Siddiqui MR, Reddy NM, Faridi HM, Shahid M, Shanley TP Metformin alleviates lung-endothelial hyperpermeability by regulating cofilin-1/PP2AC pathway. Front Pharmacol 2023;14:1211460. pii:1211460
- Zhao Y, Han X, Li C, Liu Y, Cheng J, Adhikari BK, Wang Y COVID-19 and the cardiovascular system: a study of pathophysiology and interpopulation variability. Front Microbiol 2023;14:1213111. pii:1213111
- Premkumar A, Fry JT, Bolden JR, Grobman WA, Michelson KN The value and limitations of using predetermined criteria in decision making for maternal-fetal interventions. Prenat Diagn 2023 Jun;43(6):792-797. doi:10.1002/pd.6363
- Pendergrast TR, Chapin CA, Kriegermeier AA, Pardo AC, Bass LM, Sanchez-Pinto LN Heart rate variability is associated with encephalopathy and outcomes in pediatric acute liver failure. Pediatr Res 2023 Apr;93(5):1348-1353. doi:10.1038/s41390-022-02225-2
- Rissman L, Derrington S, Michelson KN Prognostic Conversations Between Parents and Physicians in the Pediatric Intensive Care Unit. Am J Crit Care 2023 Mar 01;32(2):118-126. doi:10.4037/ajcc2023729
- Sanchez-Pinto LN, Sauthier M, Rajapreyar P, Brunow de Carvalho W, Jouvet P, Newth C, Leveraging Clinical Informatics and Data Science to Improve Care and Facilitate Research in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med 2023 Feb 01;24(12 Suppl 2):S1-S11. doi:10.1097/PCC.0000000000003155
- Divakar A, James K, Mayorga A, Michelson KN Availability of bereavement support following traumatic pediatric death in a large metropolitan area. Death Stud 2023;47(10):1127-1135. doi:10.1080/07481187.2023.2170492
- Olszewski AE, Mendelsohn L, Paquette ET Unique Ethical and Practical Considerations in the Use of Behavior Contracts for Families of Minors and Minoritized Populations in Pediatric Settings. Am J Bioeth 2023 Jan;23(1):82-85. doi:10.1080/15265161.2022.2146796
- Walker SB, Badke CM, Carroll MS, Honegger KS, Fawcett A, Weese-Mayer DE, Sanchez-Pinto LN Novel approaches to capturing and using continuous cardiorespiratory physiological data in hospitalized children. Pediatr Res 2023 Jan;93(2):396-404. doi:10.1038/s41390-022-02359-3
- Perizes EN, Chong G, Sanchez-Pinto LN Derivation and Validation of Vasoactive Inotrope Score Trajectory Groups in Critically Ill Children With Shock. Pediatr Crit Care Med 2022 Dec 01;23(12):1017-1026. doi:10.1097/PCC.0000000000003070
- Goodman DM, Casale MT, Rychlik K, Carroll MS, Auger KA, Smith TL, Cartland J, Davis MM Development and Validation of an Integrated Suite of Prediction Models for All-Cause 30-Day Readmissions of Children and Adolescents Aged 0 to 18 Years. JAMA Netw Open 2022 Nov 01;5(11):e2241513. pii:e2241513
- Zhang X, Liu SH, Geron M, Mathilda Chiu YH, Gershon R, Ho E, Huddleston K, Just AC, Kloog I, Coull BA et al. Prenatal exposure to PM2.5 and childhood cognition: Accounting for between-site heterogeneity in a pooled analysis of ECHO cohorts in the Northeastern United States. Environ Res 2022 Nov;214(Pt 4):114163. doi:10.1016/j.envres.2022.114163
- Madrigal V, MacDuffie K, Paquette ET Addressing Racism in the Healthcare Encounter: The Role of Clinical Ethics Consultants. J Clin Ethics 2022;33(3):202-209
- Koch CM, Prigge AD, Setar L, Anekalla KR, Do-Umehara HC, Abdala-Valencia H, Politanska Y, Shukla A, Chavez J, Hahn GR et al. Cilia-related gene signature in the nasal mucosa correlates with disease severity and outcomes in critical respiratory syncytial virus bronchiolitis. Front Immunol 2022;13:924792. pii:924792
- Michelson KN, Arenson M, Charleston E, Clayman ML, Brazg T, Rychlik K, Rosenberg AR, Frader J Parental Views of Social Worker and Chaplain Involvement in Care and Decision Making for Critically Ill Children with Cancer. Children (Basel) 2022 Aug 26;9(9). pii:1287
- Zhang X, Yamada Y, Sagayama H, Ainslie PN, Blaak EE, Buchowski MS, Close GL, Cooper JA, Das SK, Dugas LR et al. Human total, basal and activity energy expenditures are independent of ambient environmental temperature. iScience 2022 Aug 19;25(8):104682. pii:104682
- Paquette ET Reckoning With Redlining and Other Structural Barriers to Health of Critically Ill Children: Addressing Systemic Racism Will Require Shifting the Focus From Micro- to Macrolevel Analysis of Social Risks. Pediatr Crit Care Med 2022 Aug 01;23(8):662-665. doi:10.1097/PCC.0000000000003016
- Smith CM Late-Onset Neurologic Dysfunction in Pediatric Sepsis-What Brains Might Learn From Kidneys and Persistent Acute Kidney Injury. Pediatr Crit Care Med 2022 Aug 01;23(8):659-661. doi:10.1097/PCC.0000000000003007
- Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Correction to: Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 Aug;45(8):927. doi:10.1007/s40264-022-01199-8
- Michelson KN, Klugman CM, Kho AN, Gerke S Ethical Considerations Related to Using Machine Learning-Based Prediction of Mortality in the Pediatric Intensive Care Unit. J Pediatr 2022 Aug;247:125-128. doi:10.1016/j.jpeds.2021.12.069
- Zhang X, Lv J, Liu P, Xie X, Li X, Zhang H, Jin J Serological Measurement of Poly-IgA Immune Complex Levels in IgA Nephropathy and IgA Vasculitis. Bio Protoc 2022 Jul 05;12(13). pii:e4463
- Eickelberg G, Luo Y, Sanchez-Pinto LN Development and validation of MicrobEx: an open-source package for microbiology culture concept extraction. JAMIA Open 2022 Jul;5(2):ooac026. pii:ooac026
- Zhang X, Lucas AM, Veturi Y, Drivas TG, Bone WP, Verma A, Chung WK, Crosslin D, Denny JC, Hebbring S et al. Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders. Nat Commun 2022 Jun 14;13(1):3428. pii:3428
- Dalabih AR, Prodhan P, Harris ZL, Bone MF Employment Opportunities for Pediatric Critical Care Fellowship Trained Physicians in the United States. J Pediatr Intensive Care 2022 Jun;11(2):105-108. doi:10.1055/s-0040-1716908
- Badke CM, Carroll MS, Weese-Mayer DE, Sanchez-Pinto LN Association Between Heart Rate Variability and Inflammatory Biomarkers in Critically Ill Children. Pediatr Crit Care Med 2022 Jun 01;23(6):e289-e294. doi:10.1097/PCC.0000000000002936
- Sanchez-Pinto LN, Bennett TD Evaluation of Machine Learning Models for Clinical Prediction Problems. Pediatr Crit Care Med 2022 May 01;23(5):405-408. doi:10.1097/PCC.0000000000002942
- Zhao Y, Yu Y, Wang H, Li Y, Deng Y, Jiang G, Luo Y Machine Learning in Causal Inference: Application in Pharmacovigilance. Drug Saf 2022 May;45(5):459-476. doi:10.1007/s40264-022-01155-6
- Badke CM, Mayampurath A, Sanchez-Pinto LN Multiple Organ Dysfunction Interactions in Critically Ill Children. Front Pediatr 2022;10:874282. pii:874282
- Badke CM, Krogh-Jespersen S, Flynn RM, Shukla A, Essner BS, Malakooti MR Virtual Reality in the Pediatric Intensive Care Unit: Patient Emotional and Physiologic Responses. Front Digit Health 2022;4:867961. pii:867961
- Liu B, Yi D, Pan J, Dai J, Zhu MM, Zhao YY, Oh SP, Fallon MB, Dai Z Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension. Pulm Circ 2022 Jan;12(1):e12056. pii:e12056
- Zhang X, Moore CM, Harmacek LD, Domenico J, Rangaraj VR, Ideozu JE, Knapp JR, Woods KJ, Jump S, Jia S et al. CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons. JCI Insight 2022 Mar 22;7(6). pii:e152186