Current research projects involve studying the presence scalp swelling with accidental head trauma in infants. Other research includes examining the role of head CTs in evaluating physical abuse in infants and studying the relationship of extraaxial space size and extraaxial hemorrhage with head trauma. Multiple skull fractures and occipital skull fractures are other topics of interest.

My major research interests are developing new therapies for cystic fibrosis, characterizing and treating early lung disease in infants and young children with cystic fibrosis, improving CF care and reducing outcomes disparities in high risk patients. I am also active in healthcare quality improvement at the practice and national level.

My primary clinical and research interest is IBD (Crohn's disease and ulcerative colitis)where we are working to understand and develop a non-invasive marker of disease activity/prognosis examing nail fold caprilloscopy. I am also interested in understanding the relationship of the intestinal immune system to GI symptoms in rheumatologic disorders, specifically Juvenile Dermatomyositis.As the clinical director of the IBD program, we are involved in the international Improve Care Now network and a participating site in 3 clinical trials.

My research interests are in the areas of healthcare epidemiology and infection prevention and control, particularly Clostridium difficile infections. I am exploring various aspects of C. difficile infection, including clinical and molecular epidemiology, diagnosis, antibiotic resistance, and host immune response. The primary aims of my K23-funded translational research are to optimize the diagnosis of C. difficile infection by validating several existing and emerging diagnostic testing strategies in children with the ultimate goal of accurately differentiating C. difficile colonization and in...

Sangeeta Schroeder, M.D., Masters in Healthcare Quality and Patient Safety is an Assistant Professor of Pediatrics and has pioneered her divisions foray into creating Clinical Care Guidelines, leads a Rand Institute evaluation of AHRQs quality improvement guide at Lurie Children’s, is the quality improvement lead for a national collaborative sponsored by the American Academy of Pediatrics and is the lead on several quality improvement projects (CLABSI Reduction, Bronchiolitis, Asthma and UTI). She has presented her work at national forums including the Society of Hospital Medicine Conference a...

My research interest is the developmental origins of obesity, specifically maternal fetal programming and the identification of infants and children at high risk of developing childhood-onset obesity. My long-term goal is to facilitate early intervention to prevent obesity and type 2 diabetes mellitus.

The Sonic hedgehog signal in vertebrates is mediated by three C2H2 zinc finger transcription factors, GLI1, GLI2, and GLI3. We have shown that near identity of gene sequence exists between mouse and human GLI1 and that GLI1 functions as a transcription factor and that a critical domain in the COOH end of the protein is a transactivator with VP16-like structure. We established that GLI1 protein regulates a set of genes that coordinately control proliferation and may in part explain malignant transformation by misexpression of GLI1. We have established non-canonical activation of GLI1 by c-myc s...

Professor Craig B. Langman, is the Isaac A. Abt, MD, Professor of Kidney Diseases, and Tenured Professor of Pediatrics at the Feinberg School of Medicine, Northwestern University, Head of Kidney Diseases at the Ann and Robert H Lurie Children’s Hospital of Chicago, and director of the two Davita Children’s Dialysis Centers in Chicago. His funded research focuses on the basic and clinical expression of inherited or acquired disorders of calcium, phosphorus vitamin D, and FGF23 metabolism, mechansims of cardiovascular diseases in children with obesity or chronic kidney disease, the proteomics of...

My primary clinical interests include the care of pediatric patients with asthma, chronic lung disease and sickle cell anemia associated lung disease. My research interests include pediatric asthma with a special interest in the early evaluation of lung function changes in pediatric asthma and sickle cell disease.